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FREQUENCY

The National Health and Nutrition Examination Survey (NHANES 1999-2002) of 4392 individuals reflecting the US population reported hypothyroidism (defined as TSH levels exceeding 4.5 mIU/L) in 3.7% of the population. Regarding the subclinical hypothyroidism, estimates range between 3 and 8%. Women are more likely to develop hypothyroidism than men, and the incidence increases with age. A 2011 study conclude that about 8% of women over 50 and men over 65 in the UK suffer from an underactive thyroid. Levothyroxine, a synthetic form of thyroid hormone, is the 4th highest selling drug in the US. The number of people suffering from thyroid disorders continues to rise each year.

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