Search
Close this search box.

Thyroid Gland Follicle

The thyroid follicle (or thyroid vesicle) is the morpho-functional unit of the thyroid gland. The follicle is composed of an uni-stratified epithelium of follicular cells, which is producing thyroid hormones, disposed around a central lumen containing the colloid. The colloid is mainly composed of the precursor of thyroid hormones, the thyroglobulin. The thyroid follicle is a real trap of iodine, essential element to the functioning of the body; the ion iodide will be captured and stored in the colloid. The biosynthesis of thyroid hormones thyroxine (T4 ) and triiodothyronine (T3 ) can then take place from iodine coupling to thyroglobulin.
The thyroid follicle, outside a majority of follicular cells, contains 1 to 2 % of said parafollicular cells (or C cells) producing calcitonin. They do, however, have not contact with the colloid.

Go Back

Search

More Articles

FNA

FAN is an abreviation for Fine Needle Aspiration Biopsy. Ultrasound is used to guide a needle into a thyroid nodule suspected of cancer, removing a

Read More »

EHLERS-DANLOS Syndrome

Dr. Kurland Norbert Ehlers-Danlos syndrome (EDS) is the clinical expression of connective tissue damage (which constitutes 80% of the human body). It is of genetic

Read More »